Title: Biodegradable In Situ Forming Hydrogel for Intraocular Drug Delivery
The eye is an intricate organ, it consists of many barriers that help to protect and maintain its normal function. It is made up of two segments, the anterior segment – which includes the cornea, ciliary body, conjunctiva, sclera, and anterior uvea – and the posterior segment – which includes the retina and vitreous body. The protective design of the eye makes delivery of drugs to the back of the eye (posterior segment) difficult. However, with an ageing population, there is an increased number of blinding conditions that occur in the posterior segment that requires more effective and long-acting drug delivery systems (Mashaghi et al., 2016; Marshal, 1987).